Stem cells are progenitor cells that constitute a kind of "primordial soup" of life. Stem cells differentiate into different cell types and therefore into different organs over the course of their development.


TICEBA - Degree of differentiation


A specific type of cell that is to be found in most tissues and which is not yet determined with regard to its future form is called "pluripotent adult stem cell". These stem cells may be "programmed" by the surrounding tissue to take on any form - from heart tissue to spinal marrow neuronal cells to whole organs. These adult stem cells are found in great numbers in the skin, the biggest organ of the human organism.

Stem cells exist to replace old cells that have died off in order to guarantee the renewed function of cell groups or organs. When using autologous stem cells, no rejection occurs, as happens frequently with tissue that is strange to the body! Nothing is as compliant to the body as its own cells.

Clinical Trials

We are now also recruiting patients for further clinical studies in phase I/IIa with allogeneic ABCB5-positive (ABCB5+) mesenchymal stem cells for the following indications: chronic venous ulcers (CVU), diabetic foot ulcers (DFU) and peripheral arterial occlusive disease (PAOD). For more information click HERE.


Besides the authorization to manufacture a human medicinal product in accordance with § 13 (1) of the German Medicinal Products Act (AMG) for autologous mesenchymal stem cells, TICEBA is also authorized to manufacture a medicinal product for allogeneic mesenchymal as well as allogeneic limbal ABCB5 + stem cells following a recent extension. For more information click HERE.

The Story of Stem Cells

Review our category "The Story of Stem Cells" with the newest topic "Stem cells in wound healing" HERE.